Lox Mouse Gene Knockout Kit (CRISPR)
CAT#: KN509375
Lox - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | Lox |
Locus ID | 16948 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001286181, NM_001286182, NM_010728 |
Synonyms | AI893619; rrg; TSC-160 |
Summary | This gene encodes a precursor protein that belongs to the lysyl oxidase family of proteins. The secreted proprotein is proteolytically processed to an active mature peptide and a propeptide. This propeptide is thought to function in tumor suppression by inhibiting the Ras signaling pathway. The active enzyme plays a role in cross-linking of collagen and elastin and is essential for development of cardiovascular and respiratory systems, and development of skin and connective tissue. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN309375 | Lox - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN309375BN | Lox - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN309375LP | Lox - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN309375RB | Lox - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
GA202483 | Lox CRISPRa kit - CRISPR gene activation of mouse lysyl oxidase |
USD 1,290.00 |
{0} Product Review(s)
Be the first one to submit a review