P2rx7 Mouse Gene Knockout Kit (CRISPR)

CAT#: KN512714

P2rx7 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated.

SDS

KN2.0 knockout kit validation

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KN512714 is the updated version of KN312714.

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 2 gRNA vectors, 1 linear donor
Donor DNA EF1a-GFP-P2A-Puro
Symbol P2rx7
Locus ID 18439
Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001038839, NM_001038845, NM_001038887, NM_001284402, NM_011027
Synonyms AI467586; P2X(7); P2X7R
Summary Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells. [UniProtKB/Swiss-Prot Function]

Other Versions

SKU Description Size Price
GA203078 P2rx7 CRISPRa kit - CRISPR gene activation of mouse purinergic receptor P2X, ligand-gated ion channel, 7
    • 1 kit

USD 1,290.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.