Wt1 Mouse Gene Knockout Kit (CRISPR)
CAT#: KN519472
Wt1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN519472 is the updated version of KN319472.
USD 1,290.00
2 Weeks*
Size
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Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | Wt1 |
Locus ID | 22431 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_144783 |
Synonyms | D630046I19Rik; Wt-1 |
Summary | This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It plays an essential role in the normal development of the urogenital system, and the orthologous human gene is mutated in a small subset of patients with Wilm's tumors. Alternative splicing has been noted for this gene, however, the full-length nature of these variants is not known. The mRNA for this gene has been shown to initiate translation from non-AUG (CUG) and AUG translation start sites, resulting in different isoforms. [provided by RefSeq, Apr 2013] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA204648 | Wt1 CRISPRa kit - CRISPR gene activation of mouse Wilms tumor 1 homolog |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.