CNTF Receptor alpha (CNTFR) (NM_147164) Human Mass Spec Standard
CAT#: PH300487
CNTFR MS Standard C13 and N15-labeled recombinant protein (NP_671693)
Specifications
Product Data | |
Tag | C-Myc/DDK |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence | RC200487 |
Predicted MW | 40.6 kDa |
Protein Sequence |
>RC200487 protein sequence
Red=Cloning site Green=Tags(s) MAAPVPWACCAVLAAAAAVVYAQRHSPQEAPHVQYERLGSDVTLPCGTANWDAAVTWRVNGTDLAPDLLN GSQLVLHGLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPVLSCRSNTYPKGFYCSWHLPTPTYIPNT FNVTVLHGSKIMVCEKDPALKNRCHIRYMHLFSTIKYKVSISVSNALGHNATAITFDEFTIVKPDPPENV VARPVPSNPRRLEVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHVELSDGTAHTITDAYAGKEYIIQV AAKDNEIGTWSDWSVAAHATPWTEEPRHLTTEAQAAETTTSTTSSLAPPPTTKICDPGELGSGGGPSAPF LVSVPITLALAAAAATASSLLI TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration | 50 ug/ml as determined by BCA |
Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
Buffer | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_671693 |
RefSeq Size | 2070 |
RefSeq ORF | 1116 |
Synonyms | MGC1774 |
Locus ID | 1271 |
UniProt ID | P26992 |
Cytogenetics | 9p13.3 |
Summary | 'This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2011]' |
Protein Families | Druggable Genome |
Protein Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway |
Documents
FAQs |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC403449 | CNTFR HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC419721 | CNTFR HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY403449 | Transient overexpression lysate of ciliary neurotrophic factor receptor (CNTFR), transcript variant 1 |
USD 396.00 |
|
LY419721 | Transient overexpression lysate of ciliary neurotrophic factor receptor (CNTFR), transcript variant 2 |
USD 396.00 |
|
TP300487 | Recombinant protein of human ciliary neurotrophic factor receptor (CNTFR), transcript variant 1 |
USD 823.00 |
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