OAS1 (NM_002534) Human Mass Spec Standard
CAT#: PH300696
OAS1 MS Standard C13 and N15-labeled recombinant protein (NP_002525)
Specifications
Product Data | |
Tag | C-Myc/DDK |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence | RC200696 |
Predicted MW | 41.8 kDa |
Protein Sequence |
>RC200696 protein sequence
Red=Cloning site Green=Tags(s) MMDLRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKGGSSGKGTTL RGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFEVQAPRWGNPRALSFVLSSLQ LGEGVEFDVLPAFDALGQLTGSYKPNPQIYVKLIEECTDLQKEGEFSTCFTELQRDFLKQRPTKLKSLIR LVKHWYQNCKKKLGKLPPQYALELLTVYAWERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKN PIIEKYLRRQLTKPRPVILDPADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILLVRPP ASSLPFIPAPLHEA TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration | 50 ug/ml as determined by BCA |
Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
Buffer | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_002525 |
RefSeq Size | 1470 |
RefSeq ORF | 1092 |
Synonyms | E18/E16; IFI-4; OIAS; OIASI |
Locus ID | 4938 |
UniProt ID | P00973 |
Cytogenetics | 12q24.13 |
Summary | 'This gene is induced by interferons and encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein activates latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection and diabetes mellitus, type 1. A disease-associated allele in a splice acceptor site influences the production of the p46 splice isoform. This gene is located in a cluster of related genes on chromosome 12. [provided by RefSeq, Feb 2016]' |
Protein Families | Druggable Genome |
Documents
FAQs |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC413832 | OAS1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC419268 | OAS1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC429518 | OAS1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY413832 | Transient overexpression lysate of 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), transcript variant 1 |
USD 396.00 |
|
LY419268 | Transient overexpression lysate of 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), transcript variant 2 |
USD 396.00 |
|
LY429518 | Transient overexpression lysate of 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), transcript variant 1 |
USD 396.00 |
|
TP300696 | Recombinant protein of human 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), transcript variant 2 |
USD 823.00 |
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