RAB23 (NM_016277) Human Mass Spec Standard

CAT#: PH301922

RAB23 MS Standard C13 and N15-labeled recombinant protein (NP_057361)

Product Images

Coomassie blue staining of purified RAB23 protein (Cat# TP301922). The protein was produced from HEK293T cells transfected with RAB23 cDNA clone (Cat# RC201922) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Tag: C-Myc/DDK
• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence: RC201922
• Predicted MW: 26.7 kDa
• Protein Sequence:
  Sequence Link

  >RC201922 protein sequence
  Red=Cloning site Green=Tags(s)
  
  MLEEDMEVAIKMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRLMLWDTAGQEE
  FDAITKAYYRGAQACVLVFSTTDRESFEAVSSWREKVVAEVGDIPTVLVQNKIDLLDDSCIKNEEAEALA
  KRLKLRFYRTSVKEDLNVNEVFKYLAEKYLQKLKQQIAEDPELTHSSSNKIGVFNTSGGSHSGQNSGTLN
  GGDVINLRPNKQRTKKNRNPFSSCSIP
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: 50 ug/ml as determined by BCA
• Labeling Method: Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
• Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.

Reference Data

• RefSeq: NP_057361
• RefSeq Size: 4837
• RefSeq ORF: 711
• Synonyms: HSPC137
• Locus ID: 51715
• UniProt ID: Q9ULC3, A0A024RD41
• Cytogenetics: 6p12.1-p11.2
• Summary: This gene encodes a small GTPase of the Ras superfamily. Rab proteins are involved in the regulation of diverse cellular functions associated with intracellular membrane trafficking, including autophagy and immune response to bacterial infection. The encoded protein may play a role in central nervous system development by antagonizing sonic hedgehog signaling. Disruption of this gene has been implicated in Carpenter syndrome as well as cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
• Protein Families: Druggable Genome
• Protein Pathways: Hedgehog signaling pathway