Ku70 (XRCC6) (NM_001469) Human Mass Spec Standard

CAT#: PH304048

XRCC6 MS Standard C13 and N15-labeled recombinant protein (NP_001460)

  View other "XRCC6" proteins (3)

USD 2,055.00

3 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC204048
Predicted MW 69.8 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_001460
RefSeq Size 2284
RefSeq ORF 1827
Synonyms CTC75; CTCBF; G22P1; KU70; ML8; TLAA
Locus ID 2547
UniProt ID P12956, A0A024R1N4
Cytogenetics 22q13.2
Summary 'The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]'
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Non-homologous end-joining

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