TJP2 (NM_004817) Human Mass Spec Standard

CAT#: PH305295

TJP2 MS Standard C13 and N15-labeled recombinant protein (NP_004808)

  View other "TJP2" proteins (3)

USD 2,055.00

3 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC205295
Predicted MW 133.8 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_004808
RefSeq Size 4618
RefSeq ORF 3570
Synonyms C9DUPq21.11; DFNA51; DUP9q21.11; PFIC4; X104; ZO2
Locus ID 9414
UniProt ID Q9UDY2
Cytogenetics 9q21.11
Summary This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
Protein Pathways Tight junction, Vibrio cholerae infection

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