MARCH8 (NM_001002266) Human Mass Spec Standard

CAT#: PH305477

MARCH8 MS Standard C13 and N15-labeled recombinant protein (NP_001002266)

  View other "MARCHF8" proteins (11)

USD 2,055.00

3 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC205477
Predicted MW 32.9 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_001002266
RefSeq Size 4812
RefSeq ORF 873
Synonyms c-MIR; CMIR; MARCH-VIII; MARCH8; MIR; RNF178
Locus ID 220972
UniProt ID Q5T0T0, A0A024R7U2
Cytogenetics 10q11.21-q11.22
Summary MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003 [PubMed 12582153]; Bartee et al., 2004 [PubMed 14722266]). [supplied by OMIM, Apr 2010]
Protein Families Druggable Genome, Transmembrane

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