Metallothionein (MT1A) (NM_005946) Human Mass Spec Standard
CAT#: PH305942
MT1A MS Standard C13 and N15-labeled recombinant protein (NP_005937)
Other products for "MT1A"
Specifications
Product Data | |
Tag | C-Myc/DDK |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence | RC205942 |
Predicted MW | 6.1 kDa |
Protein Sequence |
RC205942
|
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration | 50 ug/ml as determined by BCA |
Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
Buffer | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_005937 |
RefSeq Size | 468 |
RefSeq ORF | 183 |
Synonyms | MT-1A; MT-IA; MT1; MT1S; MTC |
Locus ID | 4489 |
UniProt ID | P04731 |
Cytogenetics | 16q13 |
Summary | 'This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions. The conserved cysteine residues co-ordinate metal ions using mercaptide linkages. These proteins act as anti-oxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. Disruption of two metallothionein genes in mouse resulted in defects in protection against heavy metals, oxidative stress, immune reactions, carcinogens, and displayed obesity. [provided by RefSeq, Sep 2017]' |
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