CD42a (GP9) (NM_000174) Human Mass Spec Standard

CAT#: PH306597

GP9 MS Standard C13 and N15-labeled recombinant protein (NP_000165)

Product Images

Coomassie blue staining of purified GP9 protein (Cat# TP306597). The protein was produced from HEK293T cells transfected with GP9 cDNA clone (Cat# RC206597) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Tag: C-Myc/DDK
• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence: RC206597
• Predicted MW: 19.1 kDa
• Protein Sequence:
  Sequence Link

  >RC206597 protein sequence
  Red=Cloning site Green=Tags(s)
  
  MPAWGALFLLWATAEATKDCPSPCTCRALETMGLWVDCRGHGLTALPALPARTRHLLLANNSLQSVPPGA
  FDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRCASPSLAAHGPLGRLTGYQLGSCGWQLQ
  ASWVRPGVLWDVALVTVAALGLALLAGLLCATTEALD
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: 50 ug/ml as determined by BCA
• Labeling Method: Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
• Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.

Reference Data

• RefSeq: NP_000165
• RefSeq Size: 911
• RefSeq ORF: 531
• Synonyms: CD42a; GPIX
• Locus ID: 2815
• UniProt ID: P14770
• Cytogenetics: 3q21.3
• Summary: 'This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency. [provided by RefSeq, Oct 2008]'
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: ECM-receptor interaction, Hematopoietic cell lineage