MADH7 (SMAD7) (NM_005904) Human Mass Spec Standard

CAT#: PH310400

SMAD7 MS Standard C13 and N15-labeled recombinant protein (NP_005895)

  View other "SMAD7" proteins (3)

USD 2,055.00

3 Weeks*

Size
    • 10 ug

Product Images

Other products for "SMAD7"

Specifications

Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC210400
Predicted MW 46.2 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_005895
RefSeq Size 3103
RefSeq ORF 1278
Synonyms CRCS3; MADH7; MADH8
Locus ID 4092
UniProt ID O15105
Cytogenetics 18q21.1
Summary 'The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]'
Protein Families Druggable Genome, Transcription Factors
Protein Pathways TGF-beta signaling pathway

Documents

Other Versions

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.