PAK5 (NM_177990) Human Mass Spec Standard
CAT#: PH314173
PAK7 MS Standard C13 and N15-labeled recombinant protein (NP_817127)
Specifications
Product Data | |
Tag | C-Myc/DDK |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence | RC214173 |
Predicted MW | 80.6 kDa |
Protein Sequence |
>RC214173 representing NM_177990
Red=Cloning site Green=Tags(s) MFGKKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPKPMVDPSCITPIQLAPMKTI VRGNKPCKETSINGLLEDFDNISVTRSNSLRKESPPTPDQGASSHGPGHAEENGFITFSQYSSESDTTAD YTTEKYREKSLYGDDLDPYYRGSHAAKQNGHVMKMKHGEAYYSEVKPLKSDFARFSADYHSHLDSLSKPS EYSDLKWEYQRASSSSPLDYSFQFTPSRTAGTSGCSKESLAYSESEWGPSLDDYDRRPKSSYLNQTSPQP TMRQRSRSGSGLQEPMMPFGASAFKTHPQGHSYNSYTYPRLSEPTMCIPKVDYDRAQMVLSPPLSGSDTY PRGPAKLPQSQSKSGYSSSSHQYPSGYHKATLYHHPSLQSSSQYISTASYLSSLSLSSSTYPPPSWGSSS DQQPSRVSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRREL LFNEVVIMRDYHHDNVVDMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIATVCLSVLRALSYLH NQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYGTEVDIWSLG IMVIEMIDGEPPYFNEPPLQAMRRIRDSLPPRVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFL KLAGPPSCIVPLMRQYRHH TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration | 50 ug/ml as determined by BCA |
Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
Buffer | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_817127 |
RefSeq Size | 4506 |
RefSeq ORF | 2157 |
Synonyms | PAK7 |
Locus ID | 57144 |
UniProt ID | Q9P286, B0AZM9 |
Cytogenetics | 20p12.2 |
Summary | The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | Axon guidance, ErbB signaling pathway, Focal adhesion, Regulation of actin cytoskeleton, Renal cell carcinoma, T cell receptor signaling pathway |
Documents
FAQs |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC403606 | PAK7 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 187.00 |
|
LC412537 | PAK7 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY403606 | Transient overexpression lysate of p21 protein (Cdc42/Rac)-activated kinase 7 (PAK7), transcript variant 2 |
USD 605.00 |
|
LY412537 | Transient overexpression lysate of p21 protein (Cdc42/Rac)-activated kinase 7 (PAK7), transcript variant 1 |
USD 396.00 |
|
TP314173 | Recombinant protein of human p21 protein (Cdc42/Rac)-activated kinase 7 (PAK7), transcript variant 2 |
USD 788.00 |
|
TP723909 | Purified recombinant kinase domain protein of human p21 protein (Cdc42/Rac)-activated kinase 7 (PAK7), transcript variant 2, 10 µg |
USD 265.00 |
|
TP723910 | Purified recombinant kinase domain protein of human p21 protein (Cdc42/Rac)-activated kinase 7 (PAK7), transcript variant 2, 100 µg |
USD 820.00 |
{0} Product Review(s)
Be the first one to submit a review