Complement C3 (C3) (NM_000064) Human Mass Spec Standard

CAT#: PH315069

C3 MS Standard C13 and N15-labeled recombinant protein (NP_000055)

  View other "C3" proteins (4)

USD 2,055.00

3 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC215069
Predicted MW 187 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_000055
RefSeq Size 5067
RefSeq ORF 4989
Synonyms AHUS5; ARMD9; ASP; C3a; C3b; CPAMD1; HEL-S-62p
Locus ID 718
UniProt ID P01024, V9HWA9, B4DR57
Cytogenetics 19p13.3
Summary 'Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015]'
Protein Families Druggable Genome
Protein Pathways Complement and coagulation cascades, Systemic lupus erythematosus

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.