USP2 (NM_171997) Human Mass Spec Standard
CAT#: PH317695
USP2 MS Standard C13 and N15-labeled recombinant protein (NP_741994)
Specifications
Product Data | |
Tag | C-Myc/DDK |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence | RC217695 |
Predicted MW | 45.1 kDa |
Protein Sequence |
>RC217695 representing NM_171997
Red=Cloning site Green=Tags(s) MRTSYTVTLPEDPPAAPFPALAKELRPRSPLSPSLLLSTFVGLLLNKAKNSKSAQGLAGLRNLGNTCFMN SILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPR FVGYNQQDAQEFLRFLLDGLHNEVNRVTLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQL KSSLTCTDCGYCSTVFDPFWDLSLPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKF SIQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLREFASENTNHAVYNLYAVSNHSGTTMGGHYT AYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYELASPPSRM TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration | 50 ug/ml as determined by BCA |
Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
Buffer | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_741994 |
RefSeq Size | 1378 |
RefSeq ORF | 1188 |
Synonyms | UBP41; USP9 |
Locus ID | 9099 |
UniProt ID | O75604 |
Cytogenetics | 11q23.3 |
Summary | This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] |
Protein Families | Protease |
Documents
FAQs |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC401351 | USP2 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC403527 | USP2 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY401351 | Transient overexpression lysate of ubiquitin specific peptidase 2 (USP2), transcript variant 1 |
USD 396.00 |
|
LY403527 | Transient overexpression lysate of ubiquitin specific peptidase 2 (USP2), transcript variant 2 |
USD 396.00 |
|
TP317695 | Recombinant protein of human ubiquitin specific peptidase 2 (USP2), transcript variant 2 |
USD 748.00 |
{0} Product Review(s)
Be the first one to submit a review