QDPR (NM_000320) Human Mass Spec Standard

CAT#: PH317737

QDPR MS Standard C13 and N15-labeled recombinant protein (NP_000311)

  View other "QDPR" proteins (4)

USD 2,055.00

3 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC217737
Predicted MW 25.6 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_000311
RefSeq Size 1550
RefSeq ORF 732
Synonyms DHPR; HDHPR; PKU2; SDR33C1
Locus ID 5860
UniProt ID P09417, A0A140VKA9
Cytogenetics 4p15.32
Summary 'This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase. [provided by RefSeq, Jul 2008]'
Protein Families Druggable Genome
Protein Pathways Folate biosynthesis, Metabolic pathways

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