QDPR (NM_000320) Human Recombinant Protein
CAT#: TP720718
Purified recombinant protein of Human quinoid dihydropteridine reductase (QDPR)
Product Images
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Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
Ala2-Phe244
|
Tag | C-His |
Predicted MW | 26.8 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 um filtered solution of 20mM Tris-HCl, pH 8.0. |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_000311 |
Locus ID | 5860 |
UniProt ID | P09417, A0A140VKA9 |
Cytogenetics | 4p15.32 |
Refseq Size | 1550 |
Refseq ORF | 732 |
Synonyms | DHPR; HDHPR; PKU2; SDR33C1 |
Summary | This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome |
Protein Pathways | Folate biosynthesis, Metabolic pathways |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC424801 | QDPR HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY424801 | Transient overexpression lysate of quinoid dihydropteridine reductase (QDPR) |
USD 396.00 |
|
PH317737 | QDPR MS Standard C13 and N15-labeled recombinant protein (NP_000311) |
USD 2,055.00 |
|
TP317737 | Recombinant protein of human quinoid dihydropteridine reductase (QDPR) |
USD 748.00 |
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