FGF14 (NM_004115) Human Mass Spec Standard

CAT#: PH319002

FGF14 MS Standard C13 and N15-labeled recombinant protein (NP_004106)

Product Images

Coomassie blue staining of purified FGF14 protein (Cat# TP319002). The protein was produced from HEK293T cells transfected with FGF14 cDNA clone (Cat# RC219002) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Tag: C-Myc/DDK
• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence: RC219002
• Predicted MW: 27.5 kDa
• Protein Sequence:
  Sequence Link

  >RC219002 representing NM_004115
  Red=Cloning site Green=Tags(s)
  
  MAAAIASGLIRQKRQAREQHWDRPSASRRRSSPSKNRGLCNGNLVDIFSKVRIFGLKKRRLRRQDPQLKG
  IVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFT
  PECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPS
  LHDVGETVPKPGVTPSKSTSASAIMNGGKPVNKSKTT
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: 50 ug/ml as determined by BCA
• Labeling Method: Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
• Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.

Reference Data

• RefSeq: NP_004106
• RefSeq Size: 890
• RefSeq ORF: 741
• Synonyms: FGF-14; FHF-4; FHF4; SCA27
• Locus ID: 2259
• UniProt ID: Q92915
• Cytogenetics: 13q33.1
• Summary: 'The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]'
• Protein Families: Secreted Protein
• Protein Pathways: MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton