Rab11 (RAB11B) (NM_004218) Human Mass Spec Standard

CAT#: PH322162

RAB11B MS Standard C13 and N15-labeled recombinant protein (NP_004209)

Product Images

Coomassie blue staining of purified RAB11B protein (Cat# TP322162). The protein was produced from HEK293T cells transfected with RAB11B cDNA clone (Cat# RC222162) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Tag: C-Myc/DDK
• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence: RC222162
• Predicted MW: 24.5 kDa
• Protein Sequence:
  Sequence Link

  >RC222162 protein sequence
  Red=Cloning site Green=Tags(s)
  
  MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQ
  ERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEAR
  AFAEKNNLSFIETSALDSTNVEEAFKNILTEIYRIVSQKQIADRAAHDESPGNNVVDISVPPTTDGQKPN
  KLQCCQNL
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: 50 ug/ml as determined by BCA
• Labeling Method: Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
• Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.

Reference Data

• RefSeq: NP_004209
• RefSeq Size: 1635
• RefSeq ORF: 654
• Synonyms: H-YPT3; NDAGSCW
• Locus ID: 9230
• UniProt ID: Q15907
• Cytogenetics: 19p13.2
• Summary: The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]). [supplied by OMIM, Nov 2010]
• Protein Families: Druggable Genome
• Protein Pathways: Endocytosis