NACA (NM_001113201) Human Mass Spec Standard
CAT#: PH325258
NACA MS Standard C13 and N15-labeled recombinant protein (NP_001106672)
Specifications
Product Data | |
Tag | C-Myc/DDK |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence | RC225258 |
Predicted MW | 23.2 kDa |
Protein Sequence |
>RC225258 representing NM_001113201
Red=Cloning site Green=Tags(s) MPGEATETVPATEQELPQPQAETGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQS RSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAA EKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAI MELTM TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration | 50 ug/ml as determined by BCA |
Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
Buffer | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_001106672 |
RefSeq ORF | 645 |
Synonyms | HSD48; NAC-alpha; NACA1; skNAC |
Locus ID | 4666 |
UniProt ID | Q13765, A0A024RB41 |
Cytogenetics | 12q13.3 |
Summary | 'This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of this gene on different chromosomes. [provided by RefSeq, Feb 2016]' |
Protein Families | Druggable Genome, Transcription Factors |
Documents
FAQs |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC417201 | NACA HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC426388 | NACA HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC426389 | NACA HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY417201 | Transient overexpression lysate of nascent polypeptide-associated complex alpha subunit (NACA), transcript variant 3 |
USD 396.00 |
|
LY426388 | Transient overexpression lysate of nascent polypeptide-associated complex alpha subunit (NACA), transcript variant 2 |
USD 396.00 |
|
LY426389 | Transient overexpression lysate of nascent polypeptide-associated complex alpha subunit (NACA), transcript variant 4 |
USD 396.00 |
|
PH311268 | NACA MS Standard C13 and N15-labeled recombinant protein (NP_005585) |
USD 2,055.00 |
|
PH325257 | NACA MS Standard C13 and N15-labeled recombinant protein (NP_001106673) |
USD 2,055.00 |
|
TP311268 | Recombinant protein of human nascent polypeptide-associated complex alpha subunit (NACA), transcript variant 3 |
USD 823.00 |
|
TP325257 | Recombinant protein of human nascent polypeptide-associated complex alpha subunit (NACA), transcript variant 4 |
USD 748.00 |
|
TP325258 | Purified recombinant protein of Homo sapiens nascent polypeptide-associated complex alpha subunit (NACA), transcript variant 2 |
USD 748.00 |
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