HTRA1 Mutant (R310A, E306A) Human Recombinant Protein

CAT#: TP701130

Purified mutant recombinant protein of Human HtrA serine peptidase 1 (HTRA1), sidues 161-369aa and mutation at (R310A，E306A）

Product Images

Purified recombinant protein HTRA (R310A E306A) was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence: A DNA sequence from TrueORF clone, RC222362, residues 161-369aa of htra1_cat_R310A_E306A
• Tag: Myc-DDK
• Predicted MW: 22.5 kDa
• Concentration: >50 ug/mL as determined by microplate Bradford method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for at least 12 months from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_002766.1
• Locus ID: 5654
• Cytogenetics: 10q26.13
• Refseq Size: 2133
• Refseq ORF: 443
• Synonyms: ARMD7; CADASIL2; CARASIL; HtrA; L56; ORF480; PRSS11
• Summary: 'This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7. [provided by RefSeq, Jul 2008]'
• Protein Families: Druggable Genome, Protease, Secreted Protein