SH2B3 Mutant (R262W) Human Recombinant Protein

CAT#: TP701134

Purified mutant recombinant protein of Human SH2B adaptor protein 3 (SH2B3)，mutation at（R262W）

Product Images

Purified recombinant protein DDX58 (R262W） was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence: A DNA sequence from TrueORF clone, RC209127, encoding the full-length of FOXL2(C134W)
• Tag: DDK-His
• Predicted MW: 106.4 kDa
• Concentration: >50 ug/mL as determined by microplate Bradford method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for at least 12 months from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_055129.2
• Locus ID: 23586
• Cytogenetics: 9p21.1
• Refseq Size: 4372
• Refseq ORF: 2775
• Synonyms: RIG-I; RIG1; RIGI; RLR-1; SGMRT2
• Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response. [provided by RefSeq, Jul 2008]
• Protein Pathways: Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway