HBB Mutant (T87Q) Human Recombinant Protein

CAT#: TP701135

Purified mutant recombinant protein of Human hemoglobin, beta (HBB)，mutation at（T87Q）

Product Images

Purified recombinant protein HBB (T87Q) was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence: A DNA sequence from TrueORF clone, RC203258, encoding the full-length of HBB(T87Q)
• Tag: Myc-DDK
• Predicted MW: 15.8 kDa
• Concentration: >50 ug/mL as determined by microplate Bradford method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for at least 12 months from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_000509.1
• Locus ID: 3043
• Cytogenetics: 11p15.4
• Refseq Size: 626
• Refseq ORF: 441
• Synonyms: beta-globin; CD113t-C; ECYT6
• Summary: 'The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]'