ADAR Mutant (K744R) Human Recombinant Protein

CAT#: TP701139

Purified mutant recombinant protein of Human adenosine deaminase, RNA-specific (ADAR), transcript variant 4,mutation at(K744R)


USD 748.00

5 Days*

Size
    • 20 ug

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Specifications

Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence A DNA sequence from TrueORF clone, RC219761, encoding the full-length of ADAR(K744R)
Tag Myc-DDK
Predicted MW 103.5 kDa
Concentration >50 ug/mL as determined by microplate Bradford method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Storage Store at -80°C after receiving vials.
Stability Stable for at least 12 months from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_001020278.1
Locus ID 103
Cytogenetics 1q21.3
Refseq Size 6532
Refseq ORF 2796
Synonyms ADAR1; AGS6; DRADA; DSH; DSRAD; G1P1; IFI-4; IFI4; K88DSRBP; P136
Summary 'This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]'
Protein Families Druggable Genome
Protein Pathways Cytosolic DNA-sensing pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.