alpha skeletal muscle Actin / ACTA1 Rabbit Protein

CAT#: BA1005

alpha skeletal muscle Actin / ACTA1 rabbit protein, 0.25 mg

Product Images

Specifications

Product Data

• Species: Rabbit
• Protein Source: Skeletal muscle
• Predicted MW: 43 kDa
• Concentration: lot specific
• Purity: >98% (determined by SDS gelelectrophoresis)
• Buffer: Presentation State: Purified
  State: Lyophilized
  Buffer System: 10 mM Tris/HCl buffer pH 8.0, 0.2mM CaCl2, 0.2 mM ATP, 1 mM DTT, 0.5% (w/v) SDS
• Reconstitution: Restore with distilled water.
  BA1005S: 100 µl (final volume 100 µl).
  BA1005 : 250 µl (final volume 250 µl).
• Preparation: Lyophilized
• Applications: Protein standard in 1D and 2D SDS gelelectrophoresis.
  Immunoassays.
  Immunization.
• Protein Description: Purified Actin from Rabbit muscle.
• Note: Isoelectric Point: pI 5.4
• Storage: Store at 2-8°C (lyophilized) and at -20°C (reconstituted).
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.

Reference Data

• RefSeq: NP_001091
• Locus ID: 58
• Cytogenetics: 1q42.13
• Synonyms: ACTA; ASMA; CFTD; CFTD1; CFTDM; MPFD; NEM1; NEM2; NEM3; SHPM
• Summary: 'The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause a variety of myopathies, including nemaline myopathy, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects with manifestations such as hypotonia. [provided by RefSeq, Sep 2019]'
• Protein Families: Stem cell - Pluripotency