Neurofilament H (200 kD) Bovine Protein

CAT#: BA1014S

Neurofilament H (200 kD) bovine protein, 0.1 mg

Product Images

Specifications

Product Data

• Species: Bovine
• Protein Source: Spinal Cord
• Predicted MW: 200 kDa
• Concentration: lot specific
• Purity: >98% (determined by SDS gelelectrophoresis)
• Buffer: Presentation State: Purified
  State: Lyophilized
• Reconstitution: BA1014: Restore with 200 µl distilled water (final volume 250 μl).
  BA1014S: Restore with 80 µl distilled water (final volume 100 µl).
  Final solution: 10mM Sodium Phosphate, pH 7.5, 2mM DTT, 6M Urea, 1 mM EDTA.
• Preparation: Lyophilized
• Applications: Protein standard in 1D and 2D SDS gelelectrophoresis.
  Immunoassays.
  Immunization.
• Protein Description: Bovine Neurofilament 200 kDa
• Note: Isoelectric Point: pI 5.5
  Suitable to rebuild protofilaments and filaments under conditions of reconstitution.
• Storage: Store at 2-8°C (lyophilized) or at -20°C (reconstituted).
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.

Reference Data

• RefSeq: NP_066554
• Locus ID: 4744
• Cytogenetics: 22q12.2
• Synonyms: CMT2CC; NFH
• Summary: 'Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008]'
• Protein Families: Druggable Genome
• Protein Pathways: Amyotrophic lateral sclerosis (ALS)