Kallikrein-3 / PSA / KLK3 (PSA-ACT Complex) Human Protein

CAT#: BA1022

Kallikrein-3 / PSA / KLK3 (PSA-ACT Complex) human protein, 50 µg

Specifications

Product Data

• Species: Human
• Protein Source: Seminal Fluid
• Purity: >95% >95% purity by SDS Page
• Buffer: Presentation State: Purified
  State: Liquid purified fraction
  Buffer System: 10mM Sodium Acetate, 0.15M Sodium Chloride, pH 5.6,
  0.05% (w/v) Sodium Azide.
• Preparation: Liquid purified fraction
• Note: Caution: Status: Starting material was tested and found negative for antibodies to HIV and HBsAg. How ever, all human derived materila should be treated as potentially infectious.
• Storage: Store at 2-8°C for up to 3 weeks. For long term storage, aliquot and store at -20°C for up to one year.
• Stability: Stable for at least 3 months from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_001025218
• Locus ID: 354
• Cytogenetics: 19q13.33
• Synonyms: APS; hK3; KLK2A1; PSA
• Summary: 'Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease which is synthesized in the epithelial cells of the prostate gland, and is present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. The serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Dec 2019]'
• Protein Families: Druggable Genome, Protease, Secreted Protein
• Protein Pathways: Pathways in cancer, Prostate cancer