Ceruloplasmin Human Protein

CAT#: BA120

Ceruloplasmin human protein, 1 mg

Specifications

Product Data

• Species: Human
• Protein Source: Plasma
• Concentration: lot specific
• Purity: >95% pure by SDS-PAGE
• Buffer: Presentation State: Purified
  State: Lyophilized purified protein
  Buffer System: 50mM Potassium Phosphate, pH 6.8, 100mM Potassium Chloride, 20mM E-Amino-n-Caproic Acid and 5mM EDTA without preservatives.
  Note: Exposure to Sodium (in the form of Sodium Chloride, Sodium Phosphate, Sodium Azide as well as other Sodium containing reagents) should be avoided, as Ceruloplasmin may precipitate under these conditions. Buffers that ceruloplasmin is exposed to should be pH adjusted with Potassium Hydroxide.
  Preservative: None
• Reconstitution: Restore with distilled water.
• Preparation: Lyophilized purified protein
• Protein Description: Purified Human Plasma Ceruloplasmin.
• Note: Caution: All human source materials have tested negative for HIV 1, HIV 2, HCV and HBc antibodies and HBsAg. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infectious.
• Storage: Store the protein (in the dark) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.

Reference Data

• RefSeq: NP_000087
• Locus ID: 1356
• Cytogenetics: 3q24-q25.1
• Synonyms: CP-2
• Summary: 'The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Feb 2012]'
• Protein Families: Druggable Genome
• Protein Pathways: Porphyrin and chlorophyll metabolism