Complement C3b Human Protein

CAT#: BA150

Complement C3b human protein, 0.1 mg

Specifications

Product Data

• Species: Human
• Protein Source: Serum
• Concentration: lot specific
• Purity: >90% by SDS-PAGE
• Buffer: Presentation State: Purified
  State: Liquid purified Antigen
  Buffer System: PBS, pH 7.2
  Preservative: None
  Stabilizer: None
• Preparation: Liquid purified Antigen
• Applications: ELISA.
• Protein Description: Purified complemet component 3b (C3b) from Human serum.
  Disease status: Source serum was tested negative for HBsAg and for antibodies to HIV and HCV.
• Storage: Store (aliquotted) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.

Reference Data

• RefSeq: NP_000055
• Locus ID: 718
• Cytogenetics: 19p13.3
• Synonyms: AHUS5; ARMD9; ASP; C3a; C3b; CPAMD1; HEL-S-62p
• Summary: 'Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015]'
• Protein Families: Druggable Genome
• Protein Pathways: Complement and coagulation cascades, Systemic lupus erythematosus