Transthyretin / Prealbumin Human Protein

CAT#: BA524

Transthyretin / Prealbumin human protein, 1 mg

Specifications

Product Data

• Species: Human
• Protein Source: Plasma
• Concentration: lot specific
• Purity: >95% pure by SDS-PAGE reducing conditions.
• Buffer: Presentation State: Purified
  State: Lyophilized purified fraction.
  Buffer System: 50 mM Sodium Phosphate, pH 7.5, containing 150 mM Sodium Chloride without preservatives.
• Reconstitution: Restore with 636 µl deionized water.
• Preparation: Lyophilized purified fraction.
• Protein Description: Human Prealbumin. Significant band between 14,400 and 21,500, minor band between 31,000 and 45,000. Pattern typical of Prealbumin.
• Note: Caution: All human source materials have tested negative for HIV 1 and HIV 2 and non-reactive for anti-HCV, anti-HBc antibodies and HBsAg. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infectious.
• Storage: Store at -20°C
  Avoid repeated freezing and thawing.
• Stability: Shelf life: six months from despatch.

Reference Data

• RefSeq: NP_000362
• Locus ID: 7276
• Cytogenetics: 18q12.1
• Synonyms: ATTR; CTS; CTS1; HEL111; HsT2651; PALB; TBPA
• Summary: 'This gene encodes one of the three prealbumins, which include alpha-1-antitrypsin, transthyretin and orosomucoid. The encoded protein, transthyretin, is a homo-tetrameric carrier protein, which transports thyroid hormones in the plasma and cerebrospinal fluid. It is also involved in the transport of retinol (vitamin A) in the plasma by associating with retinol-binding protein. The protein may also be involved in other intracellular processes including proteolysis, nerve regeneration, autophagy and glucose homeostasis. Mutations in this gene are associated with amyloid deposition, predominantly affecting peripheral nerves or the heart, while a small percentage of the gene mutations are non-amyloidogenic. The mutations are implicated in the etiology of several diseases, including amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis and carpal tunnel syndrome. [provided by RefSeq, Aug 2017]'
• Protein Families: ES Cell Differentiation/IPS, Secreted Protein