Thrombospondin-1 (THBS1) Human Protein

CAT#: BA675

Thrombospondin-1 (THBS1) human protein, 25 µg

Specifications

Product Data

• Species: Human
• Protein Source: Platelets
• Concentration: lot specific
• Purity: >95% pure by SDS-PAGE
• Buffer: Presentation State: Purified
  State: Lyophilized purified protein
  Buffer System: Lyophilized from 20mM Tris, pH 8.0, containing 600mM Sodium Chloride, 2mM CaCl₂ and 20% Sucrose.
  No preservatives are added.
• Reconstitution: Restore with distilled water.
• Preparation: Lyophilized purified protein
• Protein Description: Human purified Thrombospondin.
  A cellular adhesion protein. Thrombospondin is a component of the coagulation mechanism and is believed to have potential as a marker for platelet activation and renal failure.
• Note: Caution: All human source materials have tested negative for HIV 1 and HIV 2 and non reactive for HBsAg, anti-HCV and anti-HBc by FDA approved tests. No test guarantees a product to be non-infectious.
  Therefore, all material derived from human fluids or tissues should be considered as potentially infectious.
• Storage: Store undiuted at -20°C.
  Avoid repeated freeze/thaw cycles.
• Stability: Shelf life: one year from despatch.

Reference Data

• RefSeq: NP_003237
• Locus ID: 7057
• Cytogenetics: 15q14
• Synonyms: THBS; THBS-1; TSP; TSP-1; TSP1
• Summary: 'The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis. [provided by RefSeq, Jul 2008]'
• Protein Families: Druggable Genome
• Protein Pathways: Bladder cancer, ECM-receptor interaction, Focal adhesion, p53 signaling pathway, TGF-beta signaling pathway