Collagen type II alpha 1 chain (Adult Knee Cartilage) Human Protein

CAT#: RA003

Collagen type II alpha 1 chain (Adult Knee Cartilage) human protein, 0.1 mg


USD 790.00

5 Days*

Size
    • 100 ug

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Other products for "COL2A1"

Specifications

Product Data
Species Human
Protein Source Cartilage
Concentration lot specific
Purity >98% Chromatographically and immunologically pure.
Buffer State: Liquid (sterile filtered) purified Ig fraction.
Buffer System: 0.5M Acetic Acid containing 0.01% Sodium Azide as preservative.
Preparation Liquid (sterile filtered) purified Ig fraction.
Applications Suitable for use as a control or standard in indirect trapping ELISA for quantitation of antigen in serum using a standard curve, for Immunoprecipitation and for Western blotting
Protein Description This protein has been prepared from adult human knee cartilage and is free from other collagens, human serum proteins and non-collagen extracellular matrix proteins. This product reacts with anti-Collagen Type II. Reaction with anti-Collagen I, III, IV, V or VI is negligible (typically less than 1% cross reactivity was detected by ELISA).
Storage Store vial at 2-8°C prior to opening.
This product is stable 2-8°C as an undiluted liquid.
Dilute only prior to immediate use.
Stability Shelf life: one year from despatch.
Reference Data
RefSeq NP_001835
Locus ID 1280
Cytogenetics 12q13.11
Synonyms ANFH; AOM; COL11A3; SEDC; STL1
Summary 'This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008]'
Protein Pathways ECM-receptor interaction, Focal adhesion

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.