NGF Mouse Protein

CAT#: SA003

NGF mouse protein, 1 mg

Specifications

Product Data

• Species: Mouse
• Protein Source: Submax. Glands
• Predicted MW: 13 kDa
• Concentration: lot specific
• Purity: >98% pure by SDS-PAGE.
• Buffer: State: Lyophilized purified protein.
• Reconstitution: Restore with 1.0 ml distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. We recommend that the vial is gently mixed after reconstitution.
• Preparation: Lyophilized purified protein.
• Applications: Functional Assays.
• Protein Description: Purified Natural Murine Nerve Growth Factor. Preparation: Murine nerve growth factor is prepared from the submaxillary glands of mice by a modification of the method of Bocchini and Angeletti.
• Storage: Store the antibody undiluted at 2-8°C prior to reconstitution
  and at -20°C following reconstitution.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: Six three from despatch.

Reference Data

• RefSeq: NP_002497
• Locus ID: 4803
• Cytogenetics: 1p13.2
• Synonyms: Beta-NGF; HSAN5; NGFB
• Summary: 'This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. [provided by RefSeq, Jul 2008]'
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Apoptosis, MAPK signaling pathway, Neurotrophin signaling pathway