BIRC7 / LIVIN (1-298) Human Protein

CAT#: AR03006PU-L

BIRC7 / LIVIN (1-298) human recombinant protein, 0.5 mg

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  MGSSHHHHHH SSGLVPRGSH MGPKDSAKCL HRGPQPSHWA AGDGPTQERC GPRSLGSPVL GLDTCRAWDH VDGQILGQLR PLTEEEEEEG AGATLSRGPA FPGMGSEELR LASFYDWPLT AEVPPELLAA AGFFHTGHQD KVRCFFCYGG LQSWKRGDDP WTEHAKWFPS CQFLLRSKGR DFVHSVQETH SQLLGSWDPW EEPEDAAPVA PSVPASGYPE LPTPRREVQS ESAQEPGGVS PAEAQRAWWV LEPPGARDVE AQLRRLQEER TCKVCLDRAV SIVFVPCGHL VCAECAPGLQ LCPICRAPVR SRVRTFLS
• Predicted MW: 34 kDa
• Concentration: lot specific
• Purity: >90% > 90 % by SDS PAGE
• Buffer: Presentation State: Purified
  State: Liquid protein, purified by conventional chromatography techniques
  Buffer System: 20mM Tris pH 8.0, 1mM DTT, 0.1M NaCl, 2mM EDTA, 20% glycerol
• Preparation: Liquid protein, purified by conventional chromatography techniques
• Protein Description: Recombinant human Livin fused to His-tag at N-terminus
• Note: NCBI Accession No.: NP_647478
• Storage: Store at -20 °C. Avoid repeated freezing and thawing.
• Stability: Shelf life: six months from despatch.

Reference Data

• RefSeq: NP_071444
• Locus ID: 79444
• UniProt ID: Q96CA5
• Cytogenetics: 20q13.33
• Synonyms: KIAP; LIVIN; ML-IAP; MLIAP; RNF50
• Summary: This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants [provided by RefSeq, Jul 2013]
• Protein Families: Druggable Genome