BIRC7 / LIVIN (1-298) Human Protein

CAT#: AR03006PU-L

BIRC7 / LIVIN (1-298) human recombinant protein, 0.5 mg


USD 1,105.00

2 Weeks*

Size
    • 500 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
MGSSHHHHHH SSGLVPRGSH MGPKDSAKCL HRGPQPSHWA AGDGPTQERC GPRSLGSPVL GLDTCRAWDH VDGQILGQLR PLTEEEEEEG AGATLSRGPA FPGMGSEELR LASFYDWPLT AEVPPELLAA AGFFHTGHQD KVRCFFCYGG LQSWKRGDDP WTEHAKWFPS CQFLLRSKGR DFVHSVQETH SQLLGSWDPW EEPEDAAPVA PSVPASGYPE LPTPRREVQS ESAQEPGGVS PAEAQRAWWV LEPPGARDVE AQLRRLQEER TCKVCLDRAV SIVFVPCGHL VCAECAPGLQ LCPICRAPVR SRVRTFLS
Predicted MW 34 kDa
Concentration lot specific
Purity >90% > 90 % by SDS PAGE
Buffer Presentation State: Purified
State: Liquid protein, purified by conventional chromatography techniques
Buffer System: 20mM Tris pH 8.0, 1mM DTT, 0.1M NaCl, 2mM EDTA, 20% glycerol
Preparation Liquid protein, purified by conventional chromatography techniques
Protein Description Recombinant human Livin fused to His-tag at N-terminus
Note NCBI Accession No.: NP_647478
Storage Store at -20 °C. Avoid repeated freezing and thawing.
Stability Shelf life: six months from despatch.
Reference Data
RefSeq NP_071444
Locus ID 79444
UniProt ID Q96CA5
Cytogenetics 20q13.33
Synonyms KIAP; LIVIN; ML-IAP; MLIAP; RNF50
Summary This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants [provided by RefSeq, Jul 2013]
Protein Families Druggable Genome

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.