Annexin A5 / ANXA5 Human Protein
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Specifications
Product Data | |
Species | Human |
Concentration | lot specific |
Purity | >98% by SDS PAGE/HPLC analysis |
Buffer | State: Lyophilised purified protein Buffer System: 20mM Phosphate buffered saline pH7.0 containing 0.02% Tween80 and 130mM Arginine HCl |
Reconstitution | Reconstitute with 1.0ml distilled water at 30°C for 5 minutes. |
Preparation | Lyophilised purified protein |
Applications | In vitro Assay. |
Protein Description | Recombinant Annexin V expressed in E.coli. |
Storage | Prior to reconstitution store at 2-8°C. Following reconstitution store the protein (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: 6 month from despatch. |
Reference Data | |
RefSeq | NP_001145 |
Locus ID | 308 |
UniProt ID | P08758, V9HWE0 |
Cytogenetics | 4q27 |
Synonyms | ANX5; ENX2; HEL-S-7; PP4; RPRGL3 |
Summary | 'The Annexin 5 gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. Polymorphisms in this gene have been implicated in various obstetric complications. [provided by RefSeq, Dec 2019]' |
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