Calcipressin-1 (Isoform B) (1-117) Human Protein

CAT#: AR09020PU-N

Calcipressin-1 (Isoform B) (1-117) human recombinant protein, 0.1 mg

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  MKLYFAQTLH IGSSHLAPPN PDKQFLISPP ASPPVGWKQV EDATPVINYD LLYAISKLGP GEKYELHAAT DTTPSVVVHV CESDQEKEEE EEMERMRRPK PKIIQTRRPE YTPIHLS
• Predicted MW: 13 kDa
• Concentration: lot specific
• Purity: >90% >/= 90% by SDS PAGE
• Buffer: Presentation State: Purified
  State: Liquid purified protein
  Buffer System: 20 mM Tris 7.5, 0.1 M NaCl, 1 mM DTT
• Preparation: Liquid purified protein
• Protein Description: Recombinant human DSCR1 was expressed in E.coli and purified by using conventional chromatography techniques.
• Note: NCBI Accession: NP_981962
• Storage: Store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.

Reference Data

• RefSeq: NP_001272318
• Locus ID: 1827
• UniProt ID: P53805
• Cytogenetics: 21q22.12
• Synonyms: ADAPT78; CSP1; DSC1; DSCR1; MCIP1; RCN1
• Summary: 'The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]'
• Protein Families: Transcription Factors