TANK / ITRAF (Isoform "Short" ) (1-119) Human Protein

CAT#: AR09179PU-L

TANK / ITRAF (Isoform "Short" ) (1-119) human recombinant protein, 0.5 mg


USD 765.00

2 Weeks*

Size
    • 500 ug

Product Images

Other products for "TANK"

Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
MDKNIGEQLN KAYEAFRQAC MDRDSAVKEL QQKTENYEQR IREQQEQLSL QQTIIDKLKS QLLLVNSTQD NNYGCVPLLE DSETRKNNLT LDQPQDKVIS GIAREKLPKV DIASAESSI
Predicted MW 13.6 kDa
Concentration lot specific
Purity >90% by SDS - PAGE
Buffer Presentation State: Purified
State: Liquid purified protein
Buffer System: 20 mM Tris-HCl buffer (pH 8.0)
Preparation Liquid purified protein
Protein Description Recombinant human TANK protein was expressed in E.coli and purified by using conventional chromatography techniques.
Note The sequence of this isoform differs from the canonical sequence as follows:
111-117 RRQEVSS --> DIASAES
118-425 Missing.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Reference Data
RefSeq NP_004171
Locus ID 10010
UniProt ID Q92844
Cytogenetics 2q24.2
Synonyms I-TRAF; ITRAF; TRAF2
Summary The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
Protein Families Druggable Genome
Protein Pathways RIG-I-like receptor signaling pathway

Documents

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.