6CKine / CCL21 (24-134, His-tag) Human Protein

CAT#: AR09372PU-L

6CKine / CCL21 (24-134, His-tag) human recombinant protein, 0.25 mg

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  MGSSHHHHHH SSGLVPRGSH MSDGGAQDCC LKYSQRKIPA KVVRSYRKQE PSLGCSIPAI LFLPRKRSQA ELCADPKELW VQQLMQHLDK TPSPQKPAQG CRKDRGASKT GKKGKGSKGC KRTERSQTPK GP
• Tag: His-tag
• Predicted MW: 14.5 kDa
• Concentration: lot specific
• Purity: >90% by SDS-PAGE
• Buffer: Presentation State: Purified
  State: Liquid purified protein
  Buffer System: 20 mM Tris buffer (pH 8.0) containing 10% glycerol, 1 mM DTT
• Preparation: Liquid purified protein
• Protein Description: Recombinant CCL21 protein, fused to His-tag, was expressed in E.coli and purified by using conventional chromatography techniques.
• Storage: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.

Reference Data

• RefSeq: NP_002980
• Locus ID: 6366
• Cytogenetics: 9p13.3
• Synonyms: 6Ckine; CKb9; ECL; SCYA21; SLC; TCA4
• Summary: 'This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19). [provided by RefSeq, Sep 2014]'
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction