Chagas Antigen 1F8 T. Cruzi Protein
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Other products for "AZU1"
Specifications
Product Data | |
Species | T. Cruzi |
Expression Host | E. coli |
Predicted MW | 25.8 kDa |
Concentration | lot specific |
Purity | 90-95% by 15% SDS-PAGE (Metal Affinity Chromatography). |
Buffer | Presentation State: Purified State: Lyophilized purified protein. Buffer System: 20mM HEPES, pH 8 containing 300mM Sodium Chloride, 284mM Imidazole, 2% Sucrose and ProClin300 as preservative |
Reconstitution | Restore with 0.25 ml distilled water through the septum of the tube. Centrifuge briefly (1000-2000 rpm for 5 minutes). |
Preparation | Lyophilized purified protein. |
Applications | ELISA. Lateral Flow. |
Protein Description | Recombinant Chagas Antigen 1F8 (Trypanosoma cruzi). Recombinant protein, from the IF8 epitope of Flagellar calcium-binding protein (FCABP) of Trypanosoma cruzi. Molecular weight: 25.8 kDa. Contains a 6-HIS tag. |
Storage | Store lyophilized product at 2-8°C. After reconstitution, aliquot and store at -70°C. Avoid multiple freeze/thaw cycles. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_001691 |
Locus ID | 566 |
UniProt ID | P20160 |
Cytogenetics | 19p13.3 |
Synonyms | AZAMP; AZU; CAP37; HBP; hHBP; HUMAZUR; NAZC |
Summary | 'Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. This gene encodes a preproprotein that is proteolytically processed to generate a mature azurophil granule antibiotic protein, with monocyte chemotactic and antimicrobial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. [provided by RefSeq, Nov 2015]' |
Protein Families | Druggable Genome, Protease |
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Resources
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