CD70 Human Protein
Product Images
Other products for "CD70"
Specifications
Product Data | |
Species | Human |
Expression Host | CHO |
Expression cDNA Clone or AA Sequence |
HHHHHHHHPS PGGSGGQRFA QAQQQLPLES LGWDVAELQL NHTGPQQDPR LYWQGGPALG RSFLHGPELD KGQLRIHRDG IYMVHIQVTL AICSSTTASR HHPTTLAVGI CSPASRSISL LRLSFHQGCT IASQRLTPLA RGDTLCTNLT GTLLPSRNTD ETFFGVQWVR P
|
Predicted MW | 18.8 kDa |
Purity | >95% by SDS-PAGE gel and HPLC analyses |
Buffer | Presentation State: Purified State: Lyophylized purified protein |
Bioactivity | Biological: Determined by its ability to stimulate human IL-8 production by Human PBMC using a concentration range of 10.0-25.0 ng/ml. Note: Results may vary with PBMC donors. |
Endotoxin | < 0.1 ng per μg (1EU/μg) |
Reconstitution | Restore in water to a concentration of 0.1-1.0 mg/ml. Do Not Vortex. This solution can then be diluted into other aqueous buffers and stored at 2-8°C for one week or (with a carrier protein, e.g. 0.1% BSA)) at -20°C to -80°C for longer. |
Preparation | Lyophylized purified protein |
Protein Description | Recombinant Human sCD27L contains the extracellular domain plus an N-terminal His-Tag. The calculated molecular weight of Recombinant Human sCD27L is 18.8 kDa. |
Note | Centrifuge vial before opening. |
Storage | Store the lyophilized protein at -20°C. Following reconstitution product is stable for 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freezing and thawing. |
Stability | Shelf life: One year from despatch. |
Reference Data | |
RefSeq | NP_001243 |
Locus ID | 970 |
UniProt ID | P32970, A0A0U5JA32 |
Cytogenetics | 19p13.3 |
Synonyms | CD27-L; CD27L; CD27LG; LPFS3; TNFSF7; TNLG8A |
Summary | 'The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008]' |
Protein Families | ES Cell Differentiation/IPS, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction |
Documents
FAQs |
Resources
Recombinant Protein Resources |
{0} Product Review(s)
0 Product Review(s)
Submit review
Be the first one to submit a review
Product Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.