Interleukin-28B (22-196, His-tag) Human Protein
Other products for "IFNL3"
Specifications
Product Data | |
Species | Human |
Expression cDNA Clone or AA Sequence |
VPVARLRGAL PDARGCHIAQ FKSLSPQELQ AFKRAKDALE ESLLLKDCKC RSRLFPRTWD LRQLQVRERP VALEAELALT LKVLEATADT DPALGDVLDQ PLHTLHHILS QLRACIQPQP TAGPRTRGRL HHWLHRLQEA PKKESPGCLE ASVTFNLFRL LTRDLNCVAS GDLCVHHHHH H
|
Tag | His-tag |
Predicted MW | 20.4 kDa |
Concentration | lot specific |
Purity | >85% by SDS - PAGE |
Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: Phosphate buffered saline (pH 7.4) containing 20% Glycerol, 1mM EDTA, 0.1mM PMSF |
Endotoxin | < 1.0 EU per 1 microgram of protein (determined by LAL method) |
Preparation | Liquid purified protein |
Protein Description | Recombinant human IFNL3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_001333866 |
Locus ID | 282617 |
UniProt ID | Q8IZI9, A0A0C4DGW8 |
Cytogenetics | 19q13.2 |
Synonyms | IFN-lambda-3; IFN-lambda-4; IL-28B; IL-28C; IL28B; IL28C |
Summary | This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway |
Documents
FAQs |
Resources
Recombinant Protein Resources |
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