DLK1 (24-303, His-tag) Human Protein
Other products for "DLK1"
Specifications
Product Data | |
Species | Human |
Expression Host | Insect |
Expression cDNA Clone or AA Sequence |
AECFPACNPQ NGFCEDDNVC RCQPGWQGPL CDQCVTSPGC LHGLCGEPGQ CICTDGWDGE LCDRDVRACS SAPCANNGTC VSLDDGLYEC SCAPGYSGKD CQKKDGPCVI NGSPCQHGGT CVDDEGRASH ASCLCPPGFS GNFCEIVANS CTPNPCENDG VCTDIGGDFR CRCPAGFIDK TCSRPVTNCA SSPCQNGGTC LQHTQVSYEC LCKPEFTGLT CVKKRALSPQ QVTRLPSGYG LAYRLTPGVH ELPVQQPEHR ILKVSMKELN KKTPLLTEGQ LEHHHHHH
|
Tag | His-tag |
Predicted MW | 30.7 kDa |
Concentration | lot specific |
Purity | >95% by SDS – PAGE |
Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
Endotoxin | < 1.0 EU per 1 microgram of protein (determined by LAL method) |
Preparation | Liquid purified protein |
Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_001304101 |
Locus ID | 8788 |
UniProt ID | P80370, A8K019 |
Cytogenetics | 14q32.2 |
Synonyms | Delta1; DLK; DLK-1; FA1; pG2; Pref-1; PREF1; ZOG |
Summary | This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal. [provided by RefSeq, Nov 2015] |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
Documents
FAQs |
Resources
Recombinant Protein Resources |
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