Hepatocyte growth factor / HGF Human Protein

CAT#: DA3506

Hepatocyte growth factor / HGF human recombinant protein, 5 µg


USD 190.00

2 Weeks*

Size
    • 5 ug

Product Images

Specifications

Product Data
Species Human
Expression Host Insect
Predicted MW 78 kDa
Concentration lot specific
Purity >95% pure by SDS-PAGE and visualised by silver stain.
Buffer Presentation State: Purified
State: Lyophilized without preservatives.
Buffer System: 50 mM Acetic Acid with BSA as stabilizer.
Bioactivity Biological: Human HGF is fully biologically active when compared to standards.
The activity was assayed for scattering activity in the MDCK cell assay. The ED50 was for this effect is typically at 0.5-1.0 ng/ml.
Endotoxin < 0.1 ng per µg of HGF
Reconstitution The lyophilized human HGF is soluble in water and most aqueous buffers.
It can be restored in water to a concentration of 100 µg/ml. Further dilutions should be made into buffer containing protein or medium containing serum.
Preparation Lyophilized without preservatives.
Protein Description Recombinant human HGF is a 78.0 kDa protein.
Storage The lyophilized protein is stable at -20°C for one year from despatch.
Reconstituted human HGF is stable for three months when stored in working aliquots
at -20°C.
Avoid repeated freezing and thawing.
Stability Stable for at least 3 months from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_000592
Locus ID 3082
UniProt ID P14210
Cytogenetics 7q21.11
Synonyms DFNB39; F-TCF; HGFB; HPTA; SF
Summary 'This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss. [provided by RefSeq, Nov 2015]'
Protein Families Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, Protease, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction, Focal adhesion, Melanoma, Pathways in cancer, Renal cell carcinoma

Documents

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.