HSPB1 / HSP27 Human Protein

CAT#: SA6031X

HSPB1 / HSP27 human recombinant protein, 0.5 mg


USD 620.00

2 Weeks*

Size
    • 500 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
MTERRVPFSL LRGPSWDPFR DWYPHSRLFD QAFGLPRLPE EWSQWLGGSS WPGYVRPLPP AAIESPAVAA PAYSRALSRQ LSSGVSEIRH TADRWRVSLD VNHFAPDELT VKTKDGVVEI TGKHEERQDE HGYISRCFTR KYTLPPGVDP TQVSSSLSPE GTLTVEAPMP KLATQSNEIT IPVTFESRAQ LGGPEAAKSD ETAAK
Predicted MW 22.7 kDa
Concentration lot specific
Purity >95% pure by SDS-PAGE
Buffer Presentation State: Purified
State: Liquid purified protein
Buffer System: 20 mM Hepes (pH 7.5) containing 1 mM DTT, 100 mM KCl
Endotoxin < 1.0 EU per 1µg of protein (determined by LAL method)
Preparation Liquid purified protein
Protein Description Recombinant Human Hsp27 was overexpressed in E. coli and purified by conventional chromatography.
Storage Store the antigen at 2-8°C for 1-2 weeks or (in aliquots) at -20°C to -70°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Reference Data
RefSeq NP_001531
Locus ID 3315
UniProt ID P04792, V9HW43
Cytogenetics 7q11.23
Synonyms CMT2F; HEL-S-102; HMN2B; HS.76067; Hsp25; HSP27; HSP28; SRP27
Summary 'This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. [provided by RefSeq, Aug 2017]'
Protein Pathways MAPK signaling pathway, VEGF signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.