MATK (NM_139354) Human Recombinant Protein
CAT#: TP300454
Recombinant protein of human megakaryocyte-associated tyrosine kinase (MATK), transcript variant 3
View other "MATK" proteins (9)
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Specifications
Product Data | |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
>RC200454 protein sequence
Red=Cloning site Green=Tags(s) MAGRGSLVSWRAFHGCDSAEELPRVSPRFLRAWHPPPVSARMPTRRWAPGTQCITKCEHTRPKPGELAFR KGDVVTILEACENKSWYRVKHHTSGQEGLLAAGALREREALSADPKLSLMPWFHGKISGQEAVQQLQPPE DGLFLVRESARHPGDYVLCVSFGRDVIHYRVLHRDGHLTIDEAVFFCNLMDMVEHYSKDKGAICTKLVRP KRKHGTKSAEEELARAGWLLNLQHLTLGAQIGEGEFGAVLQGEYLGQKVAVKNIKCDVTAQAFLDETAVM TKMQHENLVRLLGVILHQGLYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLESKKLVH RDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSRLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFSY GRAPYPKMSLKEVSEAVEKGYRMEPPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKLARELRSAGAPAS VSGQDADGSTSPRSQEP TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Tag | C-Myc/DDK |
Predicted MW | 51.7 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Note | For culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_647611 |
Locus ID | 4145 |
UniProt ID | P42679 |
Cytogenetics | 19p13.3 |
Refseq Size | 1940 |
Refseq ORF | 1521 |
Synonyms | CHK; CTK; HHYLTK; HYL; HYLTK; Lsk |
Summary | The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome, Protein Kinase, Stem cell - Pluripotency |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC408299 | MATK HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC408300 | MATK HEK293T cell transient overexpression lysate (as WB positive control) |
USD 187.00 |
|
LC419363 | MATK HEK293T cell transient overexpression lysate (as WB positive control) |
USD 187.00 |
|
LY408299 | Transient overexpression lysate of megakaryocyte-associated tyrosine kinase (MATK), transcript variant 3 |
USD 396.00 |
|
LY408300 | Transient overexpression lysate of megakaryocyte-associated tyrosine kinase (MATK), transcript variant 1 |
USD 605.00 |
|
LY419363 | Transient overexpression lysate of megakaryocyte-associated tyrosine kinase (MATK), transcript variant 2 |
USD 605.00 |
|
PH300454 | MATK MS Standard C13 and N15-labeled recombinant protein (NP_647611) |
USD 2,055.00 |
|
PH323161 | MATK MS Standard C13 and N15-labeled recombinant protein (NP_647612) |
USD 2,055.00 |
|
TP323161 | Recombinant protein of human megakaryocyte-associated tyrosine kinase (MATK), transcript variant 1 |
USD 748.00 |
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