CORIN (NM_006587) Human Recombinant Protein

CAT#: TP312742

Recombinant protein of human corin, serine peptidase (CORIN)

Product Images

Coomassie blue staining of purified CORIN protein (Cat# TP312742). The protein was produced from HEK293T cells transfected with CORIN cDNA clone (Cat# RC212742) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Recombinant protein was produced with TrueORF clone, RC212742. Click on the TrueORF clone link to view cDNA and protein sequences.
• Tag: C-Myc/DDK
• Predicted MW: 116.3 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Bioactivity: Enzyme activity (PMID: 27086096)
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_006578
• Locus ID: 10699
• UniProt ID: Q9Y5Q5, B4E2W9
• Cytogenetics: 4p12
• Refseq Size: 4942
• Refseq ORF: 3126
• Synonyms: ATC2; CRN; Lrp4; PEE5; TMPRSS10
• Summary: This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. The encoded protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013]
• Protein Families: Druggable Genome, Protease, Transmembrane