MAML1 (NM_014757) Human Recombinant Protein

CAT#: TP314790

Purified recombinant protein of Homo sapiens mastermind-like 1 (Drosophila) (MAML1)

Product Images

Coomassie blue staining of purified MAML1 protein (Cat# TP314790). The protein was produced from HEK293T cells transfected with MAML1 cDNA clone (Cat# RC214790) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Recombinant protein was produced with TrueORF clone, RC214790. Click on the TrueORF clone link to view cDNA and protein sequences.
• Tag: C-Myc/DDK
• Predicted MW: 107.9 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_055572
• Locus ID: 9794
• UniProt ID: Q92585
• Cytogenetics: 5q35.3
• Refseq Size: 5745
• Refseq ORF: 3048
• Synonyms: Mam-1; Mam1
• Summary: This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway. [provided by RefSeq, Jul 2008]
• Protein Pathways: Notch signaling pathway