JNK3 (MAPK10) (NM_138982) Human Recombinant Protein
CAT#: TP317188
Recombinant protein of human mitogen-activated protein kinase 10 (MAPK10), transcript variant 2
Specifications
Product Data | |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
Recombinant protein was produced with TrueORF clone, RC217188. Click on the TrueORF clone link to view cDNA and protein sequences.
|
Tag | C-Myc/DDK |
Predicted MW | 52.4 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_620448 |
Locus ID | 5602 |
UniProt ID | P53779 |
Cytogenetics | 4q21.3 |
Refseq Size | 2211 |
Refseq ORF | 1392 |
Synonyms | JNK3; JNK3A; p54bSAPK; p493F12; PRKM10; SAPK1b |
Summary | 'The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals, and thus are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system, and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]' |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | Adipocytokine signaling pathway, Colorectal cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Fc epsilon RI signaling pathway, Focal adhesion, GnRH signaling pathway, Insulin signaling pathway, MAPK signaling pathway, Neurotrophin signaling pathway, NOD-like receptor signaling pathway, Pancreatic cancer, Pathways in cancer, Progesterone-mediated oocyte maturation, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, Wnt signaling pathway |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC403373 | MAPK10 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 187.00 |
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LC419129 | MAPK10 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY403373 | Transient overexpression lysate of mitogen-activated protein kinase 10 (MAPK10), transcript variant 2 |
USD 605.00 |
|
LY419129 | Transient overexpression lysate of mitogen-activated protein kinase 10 (MAPK10), transcript variant 1 |
USD 396.00 |
|
PH307216 | MAPK10 MS Standard C13 and N15-labeled recombinant protein (NP_002744) |
USD 2,055.00 |
|
PH317188 | MAPK10 MS Standard C13 and N15-labeled recombinant protein (NP_620448) |
USD 2,055.00 |
|
TP307216 | Recombinant protein of human mitogen-activated protein kinase 10 (MAPK10), transcript variant 1 |
USD 867.00 |
|
TP760300 | Recombinant protein of human mitogen-activated protein kinase 10 (MAPK10), transcript variant 4, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug |
USD 215.00 |
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