CARD10 (NM_014550) Human Recombinant Protein

CAT#: TP317652

Recombinant protein of human caspase recruitment domain family, member 10 (CARD10)

Product Images

Coomassie blue staining of purified CARD10 protein (Cat# TP317652). The protein was produced from HEK293T cells transfected with CARD10 cDNA clone (Cat# RC217652) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Recombinant protein was produced with TrueORF clone, RC217652. Click on the TrueORF clone link to view cDNA and protein sequences.
• Tag: C-Myc/DDK
• Predicted MW: 115.8 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_055365
• Locus ID: 29775
• UniProt ID: Q9BWT7
• Cytogenetics: 22q13.1
• Refseq Size: 3912
• Refseq ORF: 3096
• Synonyms: BIMP1; CARMA3
• Summary: The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]). [supplied by OMIM, Mar 2008]