AMPD1 (NM_000036) Human Recombinant Protein

CAT#: TP317919

Recombinant protein of human adenosine monophosphate deaminase 1 (isoform M) (AMPD1)

Product Images

Coomassie blue staining of purified AMPD1 protein (Cat# TP317919). The protein was produced from HEK293T cells transfected with AMPD1 cDNA clone (Cat# RC217919) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Recombinant protein was produced with TrueORF clone, RC217919. Click on the TrueORF clone link to view cDNA and protein sequences.
• Tag: C-Myc/DDK
• Predicted MW: 90 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_000027
• Locus ID: 270
• UniProt ID: P23109
• Cytogenetics: 1p13.2
• Refseq Size: 2426
• Refseq ORF: 2241
• Synonyms: MAD; MADA; MMDD
• Summary: 'Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]'
• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Purine metabolism